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- Začetnik teme shone190
- Datum pokretanja
covek ima grip, i prepisu mu steroide ovde: mnogo je kasljao i sve ga je bolelo od naprezanja?!Otkud znaš da pomažu steroidi ? Šta si pio crni ti i koliko dugo ?
ja sam ih pio za koleno, vise ne znam, ono jes, deluju, ali ne lezi vraze, sta cu posle? i naravno da ih nisam ispio, da toi svaki dan bese pijes jednu manje? a sta ces za nedelju dana ili dve tri? evi sada me boli stopalo, sta sad treba, opet da se ganjam sa reumatologom, i onim, kako se zove za noge,. da mi nudi seckanje noktiju, kada me mucila ahilova peta?
ma pocecu ja ovaj suplement sta ima vas da nagovaram, nego vec sam uzeo DIM da pijem, resetujem se, a ovo cu da resim ionako sam u boljoj poziciji od svih vas
Poslednja izmena:
znaci, samo da vam nagovestiom o cemu se prica y videu koji reklamira PRIRODNI preparat, o PI16:
https://www.sciencegate.app/document/10.1073/pnas.1913444117
Chronic pain is a major clinical problem of which the mechanisms are incompletely understood. Here, we describe the concept that PI16, a protein of unknown function mainly produced by fibroblasts, controls neuropathic pain. The spared nerve injury (SNI) model of neuropathic pain increases PI16 protein levels in fibroblasts in dorsal root ganglia (DRG) meninges and in the epi/perineurium of the sciatic nerve. We did not detect PI16 expression in neurons or glia in spinal cord, DRG, and nerve. Mice deficient in PI16 are protected against neuropathic pain.
pa kaze:
In summary, our findings support a model in which PI16 promotes neuropathic pain by mediating a cross-talk between fibroblasts and the endothelial barrier leading to barrier opening, cellular influx, and increased pain. Its key role in neuropathic pain and its limited cellular and tissue distribution makes PI16 an attractive target for pain management.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10053226/
Chronic pain is a major source of morbidity for which there are limited effective treatments. Palmitoylethanolamide (PEA), a naturally occurring fatty acid amide, has demonstrated utility in the treatment of neuropathic and inflammatory pain. Emerging reports have supported a possible role for its use in the treatment of chronic pain, although this remains controversial. We undertook a systematic review and meta-analysis to examine the efficacy of PEA as an analgesic agent for chronic pain.
Keywords: palmitoylethanolamide, N-(2hydroxyethyl)-palmitamide, Impulsin, Palmidrol, chronic pain, analgesia, quality of life
PA KAZE
The first clinical applications of oral PEA formulations were described (using the trade name Impulsin) five decades ago in former Czechoslovakia. In 1974, Masek and colleagues published a sequence of placebo-controlled double-blind trials evaluating the use of PEA as a respiratory infection prophylactic in a population of 1386 volunteers and reported a significant reduction in pain, amount of fever episodes, and incidence of respiratory tract infections [9]. Impulsin was withdrawn from the market several years later for no apparent reason. However, oral PEA formulations continue to be available as over-the-counter dietary supplements to this day.
ZNACI ZAVERA! cilj je da se kupuju njihove droge,a ne ovo sto je prirodno. ali ni ovde nije kraj, pogldajte video... jer ako prestane da boli, opet se niste izlecili
https://www.sciencegate.app/document/10.1073/pnas.1913444117
Chronic pain is a major clinical problem of which the mechanisms are incompletely understood. Here, we describe the concept that PI16, a protein of unknown function mainly produced by fibroblasts, controls neuropathic pain. The spared nerve injury (SNI) model of neuropathic pain increases PI16 protein levels in fibroblasts in dorsal root ganglia (DRG) meninges and in the epi/perineurium of the sciatic nerve. We did not detect PI16 expression in neurons or glia in spinal cord, DRG, and nerve. Mice deficient in PI16 are protected against neuropathic pain.
pa kaze:
In summary, our findings support a model in which PI16 promotes neuropathic pain by mediating a cross-talk between fibroblasts and the endothelial barrier leading to barrier opening, cellular influx, and increased pain. Its key role in neuropathic pain and its limited cellular and tissue distribution makes PI16 an attractive target for pain management.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10053226/
Chronic pain is a major source of morbidity for which there are limited effective treatments. Palmitoylethanolamide (PEA), a naturally occurring fatty acid amide, has demonstrated utility in the treatment of neuropathic and inflammatory pain. Emerging reports have supported a possible role for its use in the treatment of chronic pain, although this remains controversial. We undertook a systematic review and meta-analysis to examine the efficacy of PEA as an analgesic agent for chronic pain.
Keywords: palmitoylethanolamide, N-(2hydroxyethyl)-palmitamide, Impulsin, Palmidrol, chronic pain, analgesia, quality of life
PA KAZE
The first clinical applications of oral PEA formulations were described (using the trade name Impulsin) five decades ago in former Czechoslovakia. In 1974, Masek and colleagues published a sequence of placebo-controlled double-blind trials evaluating the use of PEA as a respiratory infection prophylactic in a population of 1386 volunteers and reported a significant reduction in pain, amount of fever episodes, and incidence of respiratory tract infections [9]. Impulsin was withdrawn from the market several years later for no apparent reason. However, oral PEA formulations continue to be available as over-the-counter dietary supplements to this day.
ZNACI ZAVERA! cilj je da se kupuju njihove droge,a ne ovo sto je prirodno. ali ni ovde nije kraj, pogldajte video... jer ako prestane da boli, opet se niste izlecili
Poslednja izmena:
ovde ima isto odlicno objasnjeno
The Top-Rated Nerve Health Supplements of 2025
https://www.reviewscout.org/top-5-nerve-supplements/
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- 17.860
Odličan tekst
ma ja sam se zeznuo juce i porucio dynamic joint umesto nerve, pa sam im poslao e-mail ne bi li zamenili porudzbinu, a odlucio sam se jer je broj 1 cak i bolji od
samo je pitanje da li je sajt njihov reveiwscout, pa da ne lazu, ali trebalo bi da je to - to, nisam dubinski sve proveravao pa da budem bas 100% siguran
jolemisa
Buduća legenda
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- 34.642
Nedaj boze da saznas,ali kiropratktika moze mnogo da pomogne.ne moze da izleci,kao i lekovi,ali moze bar za neko vreme da te skine s lekova.